期刊论文

Expression of Ras Oncogene P 21 Protein in Benign and Malignant Diseases of the Stomach and its Correlation with Helicobacter Pylori Infection

中文

中南医学科学杂志

2095-1116

1998

2

152-154

本校为第一机构

本文Ｐ＾ｒａｓ２１免疫组化采用链霉菌抗生素蛋白－过氧化酶（ＳＰ）法检测了６１例胃粘膜标本，结果表明胃癌（５６．０％）与胃癌前病变（６０．０％）阳性率高于胃良性病变（１４．０％），Ｐ值分别〈０．０５与〈０．００５，并进行了诊断胃癌价值评估，其敏感性，特异性和准确性分别为５６．０％，６６．７．与６２．３％，说明Ｐ＾ｒａｓ２１诊断胃癌有一定价值，同时检测了幽门螺旋杆菌（ＨＰ），计算Ｐｒａｓ２１阳性与ＨＰ

The expression of ras Oncogene P 21 Protein in 61 benign and malignant diseases of the stomach was studied by streptavidin Peroxidase(SP) method.The results showed that expression of ras P 21 was higher in gastric carcinoma and early gastric carcinoma than in benign diseases.The sensitivity specificity and accuracy for diagnosing stomach cancer was 56%、66.7% and 62.5% respectively.These findings indicate that ras P 21 overexpression may be related to events of human gastric carcinomas.Helicobacter Pylori(HP) infection was assayed.The results suggest that there is a p...