On the basis of observation that singly intraveous infusion of endotoxin can result in significant injury of aorta endothelial cells of rabbits, we explored its mechanism. Both plasma concentrations of LPO (represented by MDA levels) and activities of SOD in red blood cells increased significantly, and reaching their top values 30 minutes after endotoxin administration. We suggest that endotoxin—induced endothelial injury is a...