Recent advances in ferrocene-based nanomedicines for enhanced chemodynamic therapy

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成果类型：

期刊论文

作者：

Wu, Gui-long;Tan, Senyou;Tan, Xiaofeng;Chen, Guodong*;Yang, Qinglai

通讯作者：

Chen, Guodong;Yang, QL

作者机构：

[Yang, Qinglai; Chen, Guodong; Wu, Gui-long; Tan, Senyou] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Hepatopancreatobiliary Surg, Hengyang 421001, Hunan, Peoples R China.

[Yang, Qinglai; Chen, Guodong; Wu, Gui-long; Yang, QL; Tan, Xiaofeng; Chen, GD; Tan, Senyou] Univ South China, Canc Res Inst, Ctr Mol Imaging Probe, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

[Chen, Guodong] Turpan City Peoples Hosp, Dept Gen Surg, Tulufan 838000, Peoples R China.

[Yang, QL; Chen, GD] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Yang, QL ; Chen, GD] U

Univ South China, Canc Res Inst, Ctr Mol Imaging Probe, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Enhanced Chemodynamic therapy (ECDT);Ferrocene;Nanomedicine;Synergistic therapy

期刊：

THERANOSTICS

ISSN：

1838-7640

年：

2025

卷：

期：

页码：

384-407

DOI：

10.7150/thno.101697

基金类别：

National Science Foundation of China [22374065]; Outstanding Youth Foundation of Hunan Province [2024JJ2047]; Natural Science Foundation of Hunan Province of China [2024JJ6374]; Scientific research key project of Hunan Education Department [21A0258]; Hunan Provincial Clinical Medical Technology Innovation Guide Project [2020SK51817]; University of South China Clinical Research 4310 Program [20224310NHYCG01, 20214310NHYPY05]; Xinjiang Uygur Autonomous Region Department of Science and Technology-Centralized Guided Local Science and Technology Development Fund Project [2060404]

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Malignant tumors have been a serious threat to human health with their increasing incidence. Difficulties with conventional treatments are toxicity, drug resistance, and recurrence. For this reason, non-invasive treatment modalities such as photothermal therapy (PTT), photodynamic therapy (PDT), chemodynamic therapy (CDT), and others have received much attention. Among them, Ferrocene (Fc)-based nanomedicines for enhanced Chemodynamic Therapy (ECDT) is a new therapeutic strategy based on the Fenton reaction. Based on ferrocene's good biocompatibility, potentiation in medicinal chemistry, and g...

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Recent advances in ferrocene-based nanomedicines for enhanced chemodynamic therapy

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