期刊论文

中文

环境与健康杂志

1001-5914

2005

22

1

37-39

10.16241/j.cnki.1001-5914.2005.01.015

湖南省教育厅科研项目

本校为第一机构

目的探讨烹调油烟(COF)对雄性大鼠生殖毒性作用.方法将30只雄性SD大鼠随机分为染毒组[采用半动式吸入(43±4)mg/m3烹调油烟]和对照组(吸入24～28℃加热空气),每组15只,按3个时相(20、40、60 d)观察COF对大鼠睾丸组织的病理改变以及对附睾精子畸变的影响.结果吸入COF40、60d时大鼠体重均有降低趋势;睾丸、附睾脏器与体重的比值均分别低于对照组(P＜0.05),且呈时-效关系;染毒40、60d时精子含量和存活率显著降低,畸形率增高,死亡精子明显增多,且与对照相比,差异均有统计学意义.结论烹调油烟对大鼠睾丸和附睾具有明显毒性作用.

Objective To investigate the toxic effects of inhaling cooking oil fumes(COF)on male mice. Methods 30 male SD rats were randomly divided into 2 groups, exposure group treated by inhaling COF[(43±4)mg/m3,30 min/d], control group treated by inhaling heated air (24-28℃). All of the observations and determinations were done at the day 20 th, 40 th, 60 th respectively during the experiment. At the end of the experiment, the pathologic changes of testicle tissues and rate of the sperm malfomation were detected. Results The body weight and the ratio...