期刊论文

中文

环境与健康杂志

1001-5914

1999

16

06

327-329,371

10.16241/j.cnki.1001-5914.1999.06.004

湖南省教育研究基金资助项目（97116）

本校为第一机构

探讨烹调油烟是否对肺组织具有损伤作用，采用动式吸入烹调油烟，浓度４３ ±４ ｍ ｇ／ ｍ ３ 为染毒组，吸入加热空气（２４ ～２８ ℃） 为阴性对照组，另设阳性Ｂ（ａ）Ｐ 组，每组动物１８ 只，分三个时期（２０ 天、４０ 天、６０ 天） 观察肺组织病理形态改变，检测血清和肺ＳＯＤ 活性、ＭＤＡ 及锌、铁、铜含量。烹调油烟可使血清和肺ＳＯＤ 活性明显低于阴性对照组，ＭＤＡ含量明显高于对照组（ Ｐ＜ ０－０１） ，且呈时效关系。锌、铁含量均随染毒时间延长下降，铜含量变化不明显。自由基和脂质过氧化反应及锌、铁等微量元素代谢异常可能与烹调油烟致肺组织损伤有关

To study the damage of lung tissue induced by cooking oil fume(COF),the pathomorphological varians of lung tissue were observed,and the activities of superoxidase dismutase(SOD) and the levels of malondialdehyde (MDA),zinc,iron and copper in serum and lung tissue were determined in 54 rats,which were randomly averagely devided into 3 test groups,such as exposure group dynamically inhaling (43±4)mg/m 3 COF,negative control group inhaling heated air (24~28 ℃),and positive control group infused by benzo(a)pyrene.All of the observations and deter...