Microcystin-LR induces lung injury in mice through the NF-κB/NLRP3 pathway

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhang, Yin;Guan, Ying;Dai, Manni;Yang, Yue*;Yang, Fei

通讯作者：

Yang, Yue;Yang, F;Yang, Y

作者机构：

[Zhang, Yin; Yang, F; Dai, Manni; Yang, Yue; Yang, Fei; Guan, Ying] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haza, Hengyang 421001, Peoples R China.

[Yang, Yue] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Hengyang, Hunan, Peoples R China.

[Yang, Yue] Cent Hosp Shaoyang, Dept Publ Hlth, Shaoyang, Peoples R China.

[Yang, F; Yang, Fei] Hunan Prov Maternal & Child Hlth Care Hosp, Changsha, Hunan, Peoples R China.

通讯机构：

[Yang, F ; Yang, Y] U

[Yang, Y ] C

Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haza, Hengyang 421001, Peoples R China.

Cent Hosp Shaoyang, Dept Publ Hlth, Shaoyang, Peoples R China.

Hunan Prov Maternal & Child Hlth Care Hosp, Changsha, Hunan, Peoples R China.

语种：

英文

期刊：

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

ISSN：

1528-7394

年：

2025

卷：

期：

页码：

385-394

DOI：

10.1080/15287394.2024.2443525

基金类别：

Hunan Province Key Research and Development Projects [2022SK2089]; Hunan Provincial Natural Science Youth Fund [2024JJ6392]

机构署名：

本校为第一且通讯机构

院系归属：

公共卫生学院

摘要：

Microcystin-LR (MC-LR) a cyclic toxin produced by cyanobacterial species is known to exert detrimental effects on various organs, including lung. Several investigators demonstrated that MC-LR exerts pulmonary toxicity, but the underlying mechanisms remain unclear. This study aimed to investigate whether exposure to MC-LR-induced lung inflammation and examine the underlying mechanisms. Thirty specific pathogen-free (SPF) male mice were allocated into control and MC-LR treatment groups. Mice were intraperitoneally injected with physiological saline or MC-LR (20 mu g/kg) daily for a total of 21 d...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Microcystin-LR induces lung injury in mice through the NF-κB/NLRP3 pathway

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问