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Deregulation of microRNA-193b affects the proliferation of liver cancer via myeloid cell leukemia-1

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成果类型:
期刊论文
作者:
Yin, Wenjun;Nie, Yuehua;Chen, Lingying;Wang, Quipping;Liu, Shuangquan;...
通讯作者:
He, Xiusheng;Wang, Wenjun
作者机构:
[He, Xiusheng; Yin, Wenjun] Nanhua Univ, Affiliated Hosp 1, Dept Clin Lab, 28 Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.
[Nie, Yuehua] Nanhua Univ, Affiliated Hosp 1, Dept Radiat Oncol, 28 Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.
[Chen, Lingying] Univ Southern China, Affiliated Hosp 1, Dept Blood Transfus, Hengyang 421001, Hunan, Peoples R China.
[Liu, Shuangquan; Wang, Quipping] Univ Southern China, Affiliated Hosp 1, Dept Clin Lab, Hengyang 421001, Hunan, Peoples R China.
[Wang, Wenjun] Univ Southern China, Affiliated Hosp 1, Dept Spine Surg, 69 Chuan Shan Rd, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[He, Xiusheng] N
[Wang, Wenjun] U
Nanhua Univ, Affiliated Hosp 1, Dept Clin Lab, 28 Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.
Univ Southern China, Affiliated Hosp 1, Dept Spine Surg, 69 Chuan Shan Rd, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
cell proliferation;liver cancer;microRNA-193b;myeloid cell leukemia-1
期刊:
ONCOLOGY LETTERS
ISSN:
1792-1074
年:
2018
卷:
15
期:
3
页码:
2781-2788
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81172575]; Hunan Provincial Natural Science Committee and Hengyang City Government Unification Foundation of China [12JJ9033]; Hunan Provincial Natural Science Foundation of ChinaNatural Science Foundation of Hunan Province [13JJ3079]; National Natural Science FoundationNational Natural Science Foundation of China (NSFC) [81201331]; Experimental and Clinical Study of the New Chute Screw Growing Rod System in Correction of Children with Scoliosis [2015JJ5003]
机构署名:
本校为第一且通讯机构
院系归属:
医学院
摘要:
Deregulation of microRNA (miR)-193b has been revealed to be associated with the proliferation of liver cells. However, the interaction between miR-193b and their targets inducing liver cancer remains largely unknown. The aim of the present study was to investigate the hypothesis that miR-193b affects the proliferation of liver cancer cells. In the present study, the overall survival of patients with liver cancer and low fold change of miR-193b was higher compared with that of patients with liver cancer patients and high fold change of miR-193b....

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