期刊论文

中文

Dulixue Zazhi

1002-3127

1999

13

2

88-90

10.3969/j.issn.1002-3127.1999.02.004

:湖南省教育厅科研项目

本校为第一机构

通过SD大鼠连续吸入浓度为34～50mg/m3的烹调油烟染毒,观察不同时相吸入烹调油烟对大鼠体内肺及肝组织S9组分、血清中MDA含量的变化,并观察了血液VitC含量和血清、肺及肝S9组分SOD酶活性的变化.结果表明:烹调油烟具有产生脂质过氧化的作用,可使肝、肺S9组分及血清中MDA含量增加,使血液中VitC含量减少,并使血清、肝及肺SOD酶活性降低,与阴性对照组比较,差异均有显著性(P＜0.05).烹调油烟组随着染毒时间的延长,其体内MDA逐渐增加,而SOD逐渐降低.

In order to observe oxidative lesion in of rats.Spranque dawley (SD) rats were exposed to subacute dose cooking oil fumes (COF).Rats of exposure group and negative control group inhaled COF (34～50mg/m 3×30 min/d× 20,40,60d) and hot air(25～28℃×30min/d×20,40,60d)respectively.The concentration of malondiadehyde (MDA) and the activity of superoxide dismutase (SOD) in lung and liver S 9 and in serum were tested by spectrophtometry,VitC in serum was tested,too.The results showed that COF could reduce VitC in serum significantly compared with n...