Objective: This research aimed at observing the effect of applying high-quality nursing in the intensive care unit (ICU) to esophageal cancer (EC) patients after radical resection. Methods: From January 2015 to February 2020, 155 EC patients who underwent radical resection were divided into the control group (CG; n=77) and the observation group (OG; n=78). The CG was given conventional nursing intervention, and the OG was given high-quality nursing intervention. The scores of the visual analogue scale (VAS), clinical related indexes, complicati...