Colorectal cancer (CRC) as a multifactorial disease and its causal correlations with multiple signaling pathways

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Wan, Mao-lin;Wang, Yu;Zeng, Zhi;Deng, Bo;Zhu, Bi-sheng;...

通讯作者：

Han, Qi;Wu, Qing

作者机构：

[Wan, Mao-lin] Hubei Univ Sci & Technol, Dept Hepatobiliary & Pancreat Surg, Xianning Cent Hosp, Affiliated Hosp 1, Xianning 437000, Peoples R China.

[Wang, Yu] Univ South China, Dept Lab Med, Affiliated Hosp 2, Hengyang 421001, Peoples R China.

[Zeng, Zhi] Hubei Univ Sci & Technol, Affiliated Hosp 1, Xianning Cent Hosp, Dept Pathol, Xianning 437000, Peoples R China.

[Deng, Bo; Zhu, Bi-sheng; Han, Qi] Hubei Univ Sci & Technol, Affiliated Hosp 1, Xianning Cent Hosp, Dept Oncol, Xianning 437000, Peoples R China.

[Cao, Ting; Wu, Qing] Univ South China, Affiliated Nanhua Hosp, Dept Digest Med, Hengyang 421002, Peoples R China.

通讯机构：

[Han, Qi] H

[Wu, Qing] U

Hubei Univ Sci & Technol, Affiliated Hosp 1, Xianning Cent Hosp, Dept Oncol, Xianning 437000, Peoples R China.

Univ South China, Affiliated Nanhua Hosp, Dept Digest Med, Hengyang 421002, Peoples R China.

语种：

英文

关键词：

CRC;interaction;metastasis;proliferation;signaling pathway

期刊：

BIOSCIENCE REPORTS

ISSN：

0144-8463

年：

2020

卷：

期：

页码：

BSR20200265.

DOI：

10.1042/BSR20200265

机构署名：

本校为通讯机构

院系归属：

医学院

摘要：

Abstract Colorectal cancer (CRC) is the third most common malignancy and one of the leading causes of cancer-related death among men worldwide. CRC is a multifactor digestive pathology, which is a huge problem faced not only by clinicians but also by researchers. Importantly, a unique feature of CRC is the dysregulation of molecular signaling pathways. To date, a series of reviews have indicated that different signaling pathways are disordered and have potential as therapeutic targets in CRC. Nevertheless, an overview of the function and inter...

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Colorectal cancer (CRC) as a multifactorial disease and its causal correlations with multiple signaling pathways

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