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Colorectal cancer (CRC) as a multifactorial disease and its causal correlations with multiple signaling pathways

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成果类型:
期刊论文
作者:
Wan, Mao-lin;Wang, Yu;Zeng, Zhi;Deng, Bo;Zhu, Bi-sheng;...
通讯作者:
Han, Qi;Wu, Qing
作者机构:
[Wan, Mao-lin] Hubei Univ Sci & Technol, Dept Hepatobiliary & Pancreat Surg, Xianning Cent Hosp, Affiliated Hosp 1, Xianning 437000, Peoples R China.
[Wang, Yu] Univ South China, Dept Lab Med, Affiliated Hosp 2, Hengyang 421001, Peoples R China.
[Zeng, Zhi] Hubei Univ Sci & Technol, Affiliated Hosp 1, Xianning Cent Hosp, Dept Pathol, Xianning 437000, Peoples R China.
[Deng, Bo; Zhu, Bi-sheng; Han, Qi] Hubei Univ Sci & Technol, Affiliated Hosp 1, Xianning Cent Hosp, Dept Oncol, Xianning 437000, Peoples R China.
[Cao, Ting; Wu, Qing] Univ South China, Affiliated Nanhua Hosp, Dept Digest Med, Hengyang 421002, Peoples R China.
通讯机构:
[Han, Qi] H
[Wu, Qing] U
Hubei Univ Sci & Technol, Affiliated Hosp 1, Xianning Cent Hosp, Dept Oncol, Xianning 437000, Peoples R China.
Univ South China, Affiliated Nanhua Hosp, Dept Digest Med, Hengyang 421002, Peoples R China.
语种:
英文
关键词:
CRC;interaction;metastasis;proliferation;signaling pathway
期刊:
BIOSCIENCE REPORTS
ISSN:
0144-8463
年:
2020
卷:
40
期:
3
页码:
BSR20200265.
机构署名:
本校为通讯机构
院系归属:
医学院
摘要:
Colorectal cancer (CRC) is the third most commonmalignancy and one of the leading causes of cancer-related death among men worldwide. CRC is a multifactor digestive pathology, which is a huge problem faced not only by clinicians but also by researchers. Importantly, a unique feature of CRC is the dysregulation of molecular signaling pathways. To date, a series of reviews have indicated that different signaling pathways are disordered and have potential as therapeutic targets in CRC. Nevertheless, an overview of the function and interaction of m...

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