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Impacts of ainuovirine-based and efavirenz-based antiretroviral therapies on the lipid profile of HIV/AIDS patients in southern China: a real-world study

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成果类型:
期刊论文
作者:
Zhang, Quan;Chen, Zhong;Wang, Yating;Peng, Yongquan;Tan, Si;...
通讯作者:
Wu, SJ;Wang, M
作者机构:
[Wu, Shangjie; Wu, SJ; Zhang, Quan] Cent South Univ, Xiangya Hosp 2, Dept Pulm & Crit Care Med, Changsha, Peoples R China.
[Wu, Shangjie; Wu, SJ; Zhang, Quan] Hunan Ctr Evidence based Med, Changsha, Peoples R China.
[Li, Ying; Cao, Guiying; Wang, Min; Chen, Zhong; Tan, Si] First Hosp Changsha, Inst HIV, AIDS, Changsha, Peoples R China.
[Wang, Yating; Peng, Yongquan] Univ South China, Hosp Changsha 1, Hengyang Med Sch, Grad Collaborat Training Base, Hengyang, Peoples R China.
[Bignotti, Antonia] Univ Kansas, Dept Pathol & Lab Med, Med Ctr, Kansas City, KS USA.
通讯机构:
[Wu, SJ ] C
[Wang, M ] F
Cent South Univ, Xiangya Hosp 2, Dept Pulm & Crit Care Med, Changsha, Peoples R China.
Hunan Ctr Evidence based Med, Changsha, Peoples R China.
First Hosp Changsha, Inst HIV, AIDS, Changsha, Peoples R China.
语种:
英文
关键词:
ainuovirine;efavirenz;efficacy;human immunodeficiency virus;lipid profile
期刊:
Frontiers in Medicine
ISSN:
2296-858X
年:
2024
卷:
10
页码:
1277059
基金类别:
Special Fund Program for Construction and Innovation in Hunan Province, the application of life cycle management and individualized diagnosis and treatment plans for AIDS [2020SK21361]; Hunan Provincial Administration of Traditional Chinese Medicine [D2022017]
机构署名:
本校为其他机构
摘要:
BACKGROUND: The newly approved third-generation oral anti-HIV-1 drug, ainuovirine (ANV), was used in combination with nucleoside reverse transcriptase inhibitors (NRTIs) in our study, and its effects on the lipid profile of antiretroviral-experienced HIV/AIDS patients are unclear. OBJECTIVES: This study aimed to examine the effects of antiretroviral agents on the lipid profile in patients with HIV/AIDS. METHODS: We conducted a real-world prospective study involving treatment-naive and treatment-experienced adult participants living with HIV-1 i...

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