期刊论文

Ning, Shunyan;Chen, LF

英文

Chemical Engineering Journal

1385-8947

2024

485

150022

10.1016/j.cej.2024.150022

CRediT authorship contribution statement Jing Tang: Writing – original draft, Investigation. Lingyuan Liao: Investigation, Conceptualization. Xuexiang He: Software, Data curation. Lidan Lv: Formal analysis, Data curation. Xiangbiao Yin: Resources, Methodology. Wenlong Li: Validation, Software. Yuezhou Wei: Visualization, Project administration. Shunyan Ning: Validation, Supervision, acquisition. Lifeng Chen: Writing – review & editing, Supervision, Investigation, acquisition.

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Pb-212 serves as one of the most important nuclides for targeted alpha therapy (TAT), with good potential in the treatment of malignant tumors. However, medical and clinical applications are seriously limited by its extremely short supply, which strongly depends on the acquisition of its parent nuclides such as Ra-228 or Ra-224. To address this issue, we conducted a systematic investigation on the separation of trace radium from natural thorium using the ion exchange chromatography method, and a novel porous silica-based composite resin functionalized with sulfonic acid groups was prepared, ch...