This work was financially supported by the Natural Science Foundation of Hunan Province, China (Grant No. 2021JJ70085), the National Institute of Environmental Health, the Chinese Center for Disease Control and Prevention (No. 2018shuifa25) and the Research Project of the Health Commission of Hunan Province (No. B2014134, No. B2016073, No. C20190035 and No. D202312069311).