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Therapeutic effects of the n-butanol extract of Potentilla freyniana Bornm. in hepatocellular carcinoma cells

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成果类型:
期刊论文
作者:
Wang, Yan*;Zhang, Zaiqi*;Cao, Liang*;Huang, Sisi*;Huang, Xi*;...
通讯作者:
Wang, Yan;Zhang, Zaiqi;Cao, Liang;Huang, Sisi;Huang, Xi;Zhang, Ziyang;Zhang, Yanbin;Li, Xiang
作者机构:
[Wang, Yan] College of Biology and Environmental Sciences, Jishou University, Jishou, 416000, Hunan, China. Electronic address: 1296839827@qq.com
[Zhang, Zaiqi] Hunan Provincial Key Laboratory of Dong Medicine, Hunan University of Medicine, Huaihua, 418000, Hunan, China. Electronic address: qizaizhang@126.com
[Cao, Liang] Hunan Provincial Key Laboratory of Dong Medicine, Hunan University of Medicine, Huaihua, 418000, Hunan, China. Electronic address: caoliang520945@126.com
[Huang, Sisi] College of Biology and Environmental Sciences, Jishou University, Jishou, 416000, Hunan, China. Electronic address: 2403312922@qq.com
[Huang, Xi] Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China. Electronic address: huangxi0822@163.com
通讯机构:
[Huang, Xi; Zhang, Zaiqi; Cao, Liang] H
[Huang, Sisi; Wang, Yan] C
[Zhang, Ziyang; Zhang, Yanbin] T
[Li, Xiang] S
College of Biology and Environmental Sciences, Jishou University, Jishou, 416000, Hunan, China. Electronic address:
语种:
英文
关键词:
Bioinformatics;Liver cancer;MAPK signaling pathway;Molecular docking
期刊:
Journal of Ethnopharmacology
ISSN:
0378-8741
年:
2026
卷:
354
页码:
120492
基金类别:
Acknowledgements Funding: This work was supported by Hunan Provincial Key Laboratory of Dong Medicine , Hunan University of Medicine . (2021–01). China. The Natural Science Foundation of Hunan Province ( 2023JJ30441 ). China. And the Research Foundation of TCM administration of Hunan Province , (Grant No. B2023145 ). China.
机构署名:
本校为通讯机构
摘要:
Objective This study aimed to integrate network pharmacology, bioinformatics analysis, molecular docking, and experimental validation to construct a “component–target–pathway” multidimensional network model, systematically elucidate the potential mechanisms underlying the therapeutic effects of the extract of Potentilla freyniana Bornm. (PFB) on hepatocellular carcinoma (HCC), and thereby clarify its pharmacological basis. This study aimed to integrate network pharmacology, bioinformatics analysis, molecular docking, and experimental valida...

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