Aberrant angiogenic signaling pathways: Accomplices in ovarian cancer progression and treatment

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhou, Wenchao;Zeng, Tian;Chen, Junling;Tang, Xing;Yuan, Yuwei;...

通讯作者：

Zou, J;Li, YK;Zhang, Y

作者机构：

[Hu, Daopu; Zhou, Wenchao; Zou, Juan; Zeng, Tian; Yuan, Yuwei] Univ South China, Canc Res Inst, Hengyang Med Sch, Hunan Prov Key Lab Tumor Cellular & Mol Pathol, Hengyang, Hunan, Peoples R China.

[Chen, Junling] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Gynecol, Hengyang, Hunan, Peoples R China.

[Li, Yukun; Tang, Xing; Li, YK] Cent South Univ, Zhuzhou Cent South Univ, Dept Assisted Reprod Ctr, Zhuzhou Cent Hosp,Xiangya Hosp, Zhuzhou, Hunan, Peoples R China.

[Zhang, Yue; Zhang, Y] Univ South China, Clin Anat & Reprod Med Applicat Inst, Hengyang Med Sch, Dept Histol & Embryol, Hengyang, Hunan, Peoples R China.

通讯机构：

[Zou, J ; Zhang, Y ] U

[Li, YK ] C

Univ South China, Canc Res Inst, Hengyang Med Sch, Hunan Prov Key Lab Tumor Cellular & Mol Pathol, Hengyang, Hunan, Peoples R China.

Cent South Univ, Zhuzhou Cent South Univ, Dept Assisted Reprod Ctr, Zhuzhou Cent Hosp,Xiangya Hosp, Zhuzhou, Hunan, Peoples R China.

Univ South China, Clin Anat & Reprod Med Applicat Inst, Hengyang Med Sch, Dept Histol & Embryol, Hengyang, Hunan, Peoples R China.

语种：

英文

关键词：

Angiogenesis;Inhibitor;Ovarian cancer;Pathways

期刊：

Cellular Signalling

ISSN：

0898-6568

年：

2024

卷：

120

页码：

111240

DOI：

10.1016/j.cellsig.2024.111240

基金类别：

The present study was supported by the Natural Science Foundation of HuNan Province (2021JJ50070 and 2023JJ41066), the Key Project of Scientific Research Project of HuNan Provincial Education Department (22A0317), the Natural Science Foundation of China (82303246) and the College Students' Research Learning and Innovative Experimental Project of University of South China (D202305081537225204). CRediT authorship contribution statement Wenchao Zhou: Writing – original draft. Tian Zeng: Writing – original draft. Junling Chen: Writing – original draft. Xing Tang: Data curation. Yuwei Yuan: Supervision. Daopu Hu: Methodology. Yue Zhang: Writing – review & editing. Yukun Li: Writing – review & editing, acquisition. Juan Zou: Writing – review & editing, acquisition.

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Ovarian cancer is one of the most common malignant tumors in women, and treatment options are limited. Despite efforts to adjust cancer treatment models and develop new methods, including tumor microenvironment (TME) therapy, more theoretical support is needed. Increasing attention is being given to antiangiogenic measures for TME treatment. Another important concept in ovarian cancer TME is angiogenesis, where tumor cells obtain nutrients and oxygen from surrounding tissues through blood vessels to support further expansion and metastasis. Many neovascularization signaling pathways become imb...

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Aberrant angiogenic signaling pathways: Accomplices in ovarian cancer progression and treatment

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