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Immunomodulatory Peptides for Tumor Treatment

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成果类型:
期刊论文
作者:
Song, Yang;Lei, Longtianyang;Cai, Xingyu;Wei, Hua*;Yu, Cui-Yun
通讯作者:
Wei, Hua;Yu, CY
作者机构:
[Wei, Hua; Cai, Xingyu; Yu, Cui-Yun; Lei, Longtianyang; Song, Yang; Wei, H] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dru, Sch Pharmaceut Sci, Hengyang Med Sch, Hengyang 421001, Peoples R China.
[Yu, Cui-Yun] Hunan Acad Chinese Med, Affiliated Hosp, Changsha 410013, Peoples R China.
通讯机构:
[Yu, CY ; Wei, H] U
Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dru, Sch Pharmaceut Sci, Hengyang Med Sch, Hengyang 421001, Peoples R China.
Hunan Acad Chinese Med, Affiliated Hosp, Changsha 410013, Peoples R China.
语种:
英文
关键词:
immunomodulatory peptides;peptide self-assemblies;peptide-functionalized nanocarriers
期刊:
Advanced Healthcare Materials
ISSN:
2192-2640
年:
2025
卷:
14
期:
5
页码:
e2400512
基金类别:
Key R & D Program of Hunan province; Hunan Provincial Natural Science Foundation [2023JJ50140, 2022JJ40359]; Hunan Science and Technology Innovation Leading Talent Project [2022RC3080]; [2023SK2043]; [2021SK2036]
机构署名:
本校为第一且通讯机构
院系归属:
医学院
药学与生物科学学院
摘要:
Peptides exhibit various biological activities, including biorecognition, cell targeting, and tumor penetration, and can stimulate immune cells to elicit immune responses for tumor immunotherapy. Peptide self-assemblies and peptide-functionalized nanocarriers can reduce the effect of various biological barriers and the degradation by peptidases, enhancing the efficiency of peptide delivery and improving antitumor immune responses. To date, the design and development of peptides with various functionalities have been extensively reviewed for enhanced chemotherapy; however, peptide-mediated tumo...

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