The sonoporation of ultrasound contrast agent near biological walls has received wide attention in medical fields such as targeted drug therapy. The goal of this study is to understand the probability of sonoporation generated by an ultrasound contrast agent （UCA） detached from the biological walls. A theoretical model for the single free UCA microbubble to calculate the probability of sonoporation was proposed. Based on sound reflection coefficient in biological walls in ultrasound field, the affect of sound reflection factor and driving fre...
