The Human Respiratory Microbiome Current Understandings and Future Directions

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhao, Lan;Luo, Jun-Li;Ali, Mohammed Khadem;Spiekerkoetter, Edda;Nicolls, Mark R.

通讯作者：

Nicolls, Mark R

作者机构：

[Spiekerkoetter, Edda; Zhao, Lan; Ali, Mohammed Khadem; Nicolls, Mark R.] Stanford Univ, Sch Med, Dept Med, Div Pulm Allergy & Crit Care Med, 1701 Page Mill Rd, Palo Alto, CA 94304 USA.

[Spiekerkoetter, Edda; Zhao, Lan; Ali, Mohammed Khadem; Nicolls, Mark R.] Stanford Univ, Sch Med, Vera Moulton Wall Ctr Pulm Vasc Dis, Stanford, CA 94305 USA.

[Zhao, Lan; Nicolls, Mark R.] VA Palo Alto Hlth Care Syst, Palo Alto, CA USA.

[Luo, Jun-Li] Univ South China, Hengyang Med Sch, Canc Res Inst, Hengyang, Peoples R China.

语种：

英文

关键词：

Microbial metabolites;Microbiome;Mucus;Respiratory diseases;Therapeutics

期刊：

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

ISSN：

1044-1549

年：

2023

卷：

期：

页码：

245-255

DOI：

10.1165/rcmb.2022-0208TR

基金类别：

Supported by the Foundation for the National Institutes of Health grants HL095686 and HL158714; AMVETS grant BX005628; and Division Chief Startup Funds.

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Microorganisms colonize the human body. The lungs and respiratory tract, previously believed to be sterile, harbor diverse microbial communities and the genomes of bacteria (bacteriome), viruses (virome), and fungi (mycobiome). Recent advances in amplicon and shotgun metagenomic sequencing technologies and data-analyzing methods have greatly aided the identification and characterization of microbial populations from airways. The respiratory microbiome has been shown to play roles in human health and disease and is an area of rapidly emerging in...

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