期刊论文

Liu, Yi;Yang, ZeHua;Zheng, Xing

英文

Natural Product Communications

1934-578X

2019

14

9

10.1177/1934578X19878921

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the National Natural Science Foundation (81273537), Hunan Provincial Hengyang Joint Fund (2017JJ4050), Hunan graduate science and technology innovation projects (CX2018B585), the Natural Science Foundation of Hunan Province (2018JJ3426); the young and middle-aged innovative personnel training project of the Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study (0223-0002-0002000-52); the undergraduate research learning and innovative experiment project (2018XJXZ199, 2018XJXZ349); the guiding project of Hengyang Science and Technology Department (S2018F9031015299), Program for Innovative talent team of Hengyang (2017-1), the Key Project of Hengyang Science and Technology Department (2017KJ166).

本校为第一且通讯机构

Chrysin, a flavonoid, has played a great role in the fields of anticancer, antibacterial, and antiviral drug discovery. A large number of chrysin derivatives have been synthesized recently. The fluorine atom represents an important substituent group for a great number of natural products and pharmaceuticals. Taking into account the importance of both chrysin and the fluorine atom in medicinal chemistry, the synthesis of fluorine-containing chrysin derivatives has gained great interest. Chemically, the synthetic methods for these new chrysin derivatives have also been developed rapidly. In rece...