Neuroprotective effect of the traditional decoction Tian-Si-Yin against Alzheimer\'s disease via suppression of neuroinflammation - 成果

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Neuroprotective effect of the traditional decoction Tian-Si-Yin against Alzheimer's disease via suppression of neuroinflammation

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhou, Ling;Yang, Chunqing;Liu, Zhiqiang;Chen, Linlin;Wang, Ping;...

通讯作者：

Wang, XR;Zhu, LQ;Zhou, LT

作者机构：

[Yang, Chunqing; Zhou, Ling; Liu, Zhiqiang; Zhu, Ling-Qiang] Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Basic Med, Key Lab Neurol Disorders,Educ Minist,Dept Pathophy, Wuhan, Peoples R China.

[Chen, Linlin; Wang, Ping] Hubei Univ Chinese Med, Sch Basic Med, Wuhan, Peoples R China.

[Zhou, Yuan; Yuan, Mei] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Neurol, Hengyang, Peoples R China.

[Zhou, Lan-Ting] Hubei Univ Arts & Sci, Sch Basic Med, Xiangyang, Peoples R China.

[Zhou, Lan-Ting] Hubei Univ Arts & Sci, Xiangyang Cent Hosp, Affiliated Hosp, Neurosci & Brainscience Inst, Xiangyang, Peoples R China.

通讯机构：

[Zhu, LQ ; Zhou, LT ] H

[Wang, XR ] S

Shanxi Bethune Hosp, Dept Anesthesiol, Taiyuan, Peoples R China.

Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Pathophysiol, 13 Hangkong Rd, Wuhan 430030, Peoples R China.

Hubei Univ Arts & Sci, Sch Basic Med, 296 Longzhong Rd, Xiangyang 441053, Peoples R China.

语种：

英文

关键词：

Alzheimer's disease;Network pharmacology;Proteomics;Tian-Si-Yin

期刊：

Journal of Ethnopharmacology

ISSN：

0378-8741

年：

2024

卷：

321

页码：

117569

DOI：

10.1016/j.jep.2023.117569

基金类别：

Major Project of "Brain Science and Brain-inspired Research" [STI2030-Major Projects-2022ZD0211800]; National Natural Science Foundation of China [82325017, 82261138555, 82030032, 32070960, 31721002, 82001164]; Natural Science Foundation of Hubei Province [2022CFA004, 2023AFA068]; Science and technology innovation Program of Hunan Province [2022RC4044]; Top-Notch Young Talents Program of China; Teachers' Scientific Ability Cultivation Foundation of Hubei University of Arts and Science [2021kpgpzk03]; University of South China Clinical Research 4310 Program [2023NBI07]; China Postdoctoral Science Foundation; Neuroscience and Brain science Institute of Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science; [20224310NHYCG08]; [2021M691153]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

ETHNOPHARMACOLOGICAL RELEVANCE: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease among old adults. As a traditional Chinese medicine, the herbal decoction Tian-Si-Yin consists of Morinda officinalis How. and Cuscuta chinensis Lam., which has been widely used to nourish kidney. Interestingly, Tian-Si-Yin has also been used to treat dementia, depression and other neurological conditions. However, its therapeutic potential for neurodegenerative diseases such as AD and the underlying mechanisms remain unclear. AIM OF THE STU...

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Neuroprotective effect of the traditional decoction Tian-Si-Yin against Alzheimer's disease via suppression of neuroinflammation

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