[Zhou, Jing; Yao, Xu; Xiang, Yi-Jun; Liu, Shun] Univ South China, Inst Pharm & Pharmacol, Hunan Prov Key Lab Tumor Microenvironm Respons Dru, Hengyang 421001, Peoples R China.

[Lin, Jin-Hong; Xiao, Ji-Chang; Xiang, Yi-Jun] Chinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China.

[Lin, Jin-Hong] Shanghai Univ, Innovat Drug Res Ctr, Dept Chem, Shanghai 200444, Peoples R China.

[Jin-Hong Lin; Ji-Chang Xiao] K

[Xu Yao] I

Institute of Pharmacy and Pharmacology, Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, University of South China, 421001 Hengyang, PR China<&wdkj&>Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, 200032 Shanghai, PR China<&wdkj&>Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, 200032 Shanghai, PR China<&wdkj&>Department of Chemistry, Innovative Drug Research Center, Shanghai University, 200444 Shanghai, PR China

Organic compounds;Alkyl alcohols;Allyl alcohols;Benzyl alcohol;Higher yield;Pharmaceutical chemistry;Propargyl alcohol;Protocol cans;Sulfinates;Sulfonyl groups;Sulfonylation;Chemical reactions;(3 phenylprop 2 ynylsulfonyl)benzene;1 (cinnamylsulfonyl) 4 nitrobenzene;1 bromo 4 [1 [(trifluoromethyl)sulfonyl]ethyl]benzene;1 bromo 4 [[(4 trifluoromethyl)sulfonyl]methyl]benzene;1 chloro 4 (cinnamylsulfonyl)benzene;1 chloro 4 [(3 phenylprop 2 yn 1 yl)sulfonyl]benzene;1 chloro 4 [(4 phenylbutyl)sulfonyl]benzene;1 iodo 2 [[(trifluoromethyl)sulfonyl]methyl]benzene;1 methoxy 3 [(phenylsulfonyl)methyl]benzene;1 methoxy 3 [[(trifluoromethyl)sulfonyl]methyl]benzene;1 [[(difluoromethyl)sulfonyl]methyl] 3 methoxybenzene;1,3 dichloro 2 [[(trifluoromethyl)sulfonyl]methyl]benzene;1,3,5 trimethyl 2 [[(trifluoromethyl)sulfonyl]methyl]benzene;2 [1 [(trifluoromethyl)sulfonyl]ethyl]naphthalene;2 [[(difluoromethyl)sulfonyl]methyl]benzo[b]thiophene;2 [[(trifluoromethyl)sulfonyl]methyl]benzofuran;2 [[(trifluoromethyl)sulfonyl]methyl]benzo[b]thiophene;2,3 dimethoxy 5 methyl 6 [10 (phenylsulfonyl)decyl]cyclohexa 2,5 diene 1,4 dione;2,3 dimethoxy 5 methyl 6 [10 [(trifluoromethyl)sulfonyl]decyl]cyclohexa 2,5 diene 1,4 dione;4 (methoxycarbonyl)benzyl phenyl sulfone;4 (methoxycarbonyl)benzyl triflone;4 (tosylmethyl) 1,1' biphenyl;4 trifluoromethylphenylmethyl trifluoromethyl sulfone;4 [(cyclopropylsulfonyl)methyl] 1,1' biphenyl;4 [(phenylsulfonyl)methyl] 1,1' biphenyl;4 [[(4 chlorophenyl)sulfonyl]methyl] 1,1' biphenyl;4 [[(4 nitrophenyl)sulfonyl]methyl] 1,1' biphenyl;4 [[(difluoromethyl)sulfonyl]methyl] 1,1' biphenyl;4 [[(trifluoromethyl)sulfonyl]methyl] 1,1' biphenyl;5 [[(trifluoromethyl)sulfonyl]methyl]benzo[d][1,3]dioxole;alcohol derivative;chloro 4 (undec 10 en 1 ylsulfonyl)benzene;cinnamylsulfonylbenzene;methyl 4 [[(difluoromethyl)sulfonyl]methyl]benzoate;n [4 (4 fluorophenyl) 6 isopropyl 5 [[(trifluoromethyl)sulfonyl]methyl]pyrimidin 2 yl] n methylmethanesulfonamide;sulfone derivative;unclassified drug;[(4 phenylbutyl)sulfonyl]benzene;[3 (cyclopropylsulfonyl)prop 1 en 1 yl]benzene;[3 (cyclopropylsulfonyl)prop 1 yn 1 yl]benzene;[3 (trifluoromethyl)sulfonyl]prop 1 en 1 yl)benzene;[3 [(difluoromethyl)sulfonyl]prop 1 en 1 yl]benzene;[4 [(trifluoromethyl)sulfonyl]butyl]benzene;Article;controlled study;dehydroxylative sulfonylation;electrophilicity;hydroxylation;medicinal chemistry;nuclear magnetic resonance spectroscopy;nucleophilicity;racemization;reaction analysis;reaction optimization;reaction temperature;reaction time

药学与生物科学学院