Dehydroxylative Sulfonylation of Alcohols

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xiang, Yi-Jun;Liu, Shun;Zhou, Jing;Lin, Jin-Hong;Yao, Xu;...

通讯作者：

Jin-Hong Lin<&wdkj&>Xu Yao<&wdkj&>Ji-Chang Xiao

作者机构：

[Zhou, Jing; Yao, Xu; Xiang, Yi-Jun; Liu, Shun] Univ South China, Inst Pharm & Pharmacol, Hunan Prov Key Lab Tumor Microenvironm Respons Dru, Hengyang 421001, Peoples R China.

[Lin, Jin-Hong; Xiao, Ji-Chang; Xiang, Yi-Jun] Chinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China.

[Lin, Jin-Hong] Shanghai Univ, Innovat Drug Res Ctr, Dept Chem, Shanghai 200444, Peoples R China.

通讯机构：

[Jin-Hong Lin; Ji-Chang Xiao] K

[Xu Yao] I

Institute of Pharmacy and Pharmacology, Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, University of South China, 421001 Hengyang, PR China<&wdkj&>Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, 200032 Shanghai, PR China<&wdkj&>Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, 200032 Shanghai, PR China<&wdkj&>Department of Chemistry, Innovative Drug Research Center, Shanghai University, 200444 Shanghai, PR China

语种：

英文

期刊：

JOURNAL OF ORGANIC CHEMISTRY

ISSN：

0022-3263

年：

2023

卷：

期：

页码：

4818-4828

DOI：

10.1021/acs.joc.2c03085

基金类别：

National Key Research and Development Program of China [2021YFF0701700]; National Natural Science Foundation [21971252, 21991122, 22271181]; Science and Technology Commission of Shanghai Municipality [22ZR1423600]; Undergraduate Research Learning and Innovative Experiment Project [220XCX105, 220XCX310, 220XCX294, S202110555237, S202110555248, X202110555454, 202150083704]; Laboratory of Tea and Health of Hengyang; [X202110555464]

机构署名：

本校为第一机构

院系归属：

药学与生物科学学院

摘要：

Described here is the R3P/ICH2CH2I-promoted dehydroxylative sulfonylation of alcohols with a variety of sulfinates. In contrast to previous dehydroxylative sulfonylation methods, which are usually limited to active alcohols, such as benzyl, allyl, and propargyl alcohols, our protocol can be extended to both active and inactive alcohols (alkyl alcohols). Various sulfonyl groups can be incorporated, such as CF3SO2 and HCF2SO2, which are fluorinated groups of interest in pharmaceutical chemistry and the installation of which has received increasing attention. Notably, all reagents are cheap and w...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Dehydroxylative Sulfonylation of Alcohols

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问