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A new anthraquinone and a new naphthoquinone from the whole plant of Spermacoce latifolia

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成果类型:
期刊论文
作者:
Luo, Ying;Shen, Hai-Yan;Shen, Qing-Xiang;Cao, Zhao-Hui;Zhang, Min;...
通讯作者:
Tan, Jian-Wen
作者机构:
[Luo, Ying; Long, Shi-Yin; Wang, Zong-Bao; Cao, Zhao-Hui; Zhang, Min] Univ South China, Sch Pharm & Biol Sci, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hunan Prov Educ Dept, Hengyang 421001, Peoples R China.
[Luo, Ying; Tan, Jian-Wen] Chinese Acad Sci, South China Bot Garden, Guangdong Prov Key Lab Appl Bot, Guangzhou 510650, Guangdong, Peoples R China.
[Shen, Hai-Yan] Univ South China, Inst Pathogen Biol, Hengyang 421001, Peoples R China.
[Shen, Qing-Xiang] Univ South China, Affiliated Hosp 2, Dept Obstet & Gynaecol, Hengyang 421001, Peoples R China.
通讯机构:
[Tan, Jian-Wen] C
Chinese Acad Sci, South China Bot Garden, Guangdong Prov Key Lab Appl Bot, Guangzhou 510650, Guangdong, Peoples R China.
语种:
英文
关键词:
Rubiaceae;Spermacoce latifolia;anthraquinone;antibacterial activity;naphthoquinone;alpha-glucosidase inhibitor
期刊:
亚洲天然物产研究(英文版)
ISSN:
1028-6020
年:
2017
卷:
19
期:
9
页码:
869-876
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31270406]; Project of Health and Family Planning Commission of Hunan Province [C2017016]; Science and Technology Development Program of Hengyang City [2016KJ61]; Key Project of the Office of Science Education in Hunan Province [16A186]
机构署名:
本校为第一机构
院系归属:
医学院
药学与生物科学学院
摘要:
A phytochemical study on the whole plant of Spermacoce latifolia led to the isolation of a new anthraquinone, 1,2,6-trihydroxy-5-methoxy-9,10-anthraquinone (1), and a new naphthoquinone, (2R)-6-hydroxy-7-methoxy-dehydroiso-α-lapachone (2), together with three known anthraquinones (3–5). Their structures were established on the basis of detailed spectroscopic analysis, including one- and two-dimensional NMR, ESI–MS, and HR–ESI–MS techniques. All the compounds were isolated from S. latifolia for the first time. Compounds 1, 2, 4, and 5 showe...

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