This study was carried out to explore the moderating effect of comic education and locus of control (LOC) in innovation and entrepreneurship education in colleges and universities. Firstly, the theoretical knowledge of comic education, innovation and entrepreneurship education, and LOC was briefly introduced, and the significance of comics for innovation and entrepreneurship education was discussed. Secondly, the existing innovation and entrepreneurship education modes in colleges and universities in China were introduced. Thirdly, a simple com...