Urocanic acid facilitates acquisition of object recognition memory in mice

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成果类型：

期刊论文

作者：

Wang, Le;Tan, Yinna;Wang, Hao;Yu, Xu-Dong;Mo, Yanxin;...

通讯作者：

Zhiming He<&wdkj&>Xinhua Shu

作者机构：

[Yu, Xu-Dong; Mo, Yanxin; Wang, Le; He, Zhiming; Shu, Xinhua; Wang, Hao] Shaoyang Univ, Pu Ai Med Sch, Shaoyang 422000, Peoples R China.

[Tan, Yinna] Univ South China, Affiliated Nanhua Hosp, Hengyang Med Sch, Anesthesiol Dept, Hengyang 421000, Peoples R China.

[Shu, Xinhua; Reilly, James] Glasgow Caledonian Univ, Dept Biol & Biomed Sci, Glasgow G4 0BA, Scotland.

[Shu, Xinhua] Glasgow Caledonian Univ, Dept Vis Sci, Glasgow G4 0BA, Scotland.

通讯机构：

[Zhiming He; Xinhua Shu] P

Pu Ai Medical School, Shaoyang University, Shaoyang 422000, P.R. China<&wdkj&>Pu Ai Medical School, Shaoyang University, Shaoyang 422000, P.R. China<&wdkj&>Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow G4 0BA, United Kingdom<&wdkj&>Department of Vision Science, Glasgow Caledonian University, Glasgow G4 0BA, United Kingdom

语种：

英文

关键词：

Urocanic acid;Memory acquisition;Long-term memory;Short-term memory;Location recognition;Object recognition

期刊：

Physiology & Behavior

ISSN：

0031-9384

年：

2023

卷：

266

页码：

114201

DOI：

10.1016/j.physbeh.2023.114201

基金类别：

Locus Scholarship Programme of Hunan Province, China; TENOVUS Scotland; Natural Science Foundation of Hunan Province [202210547024]; Hunan Provincial Health Commission [19A449]; National College Students Innovation and Entrepreneurship Training Program [2019-23, S20-02]; Department of Education, Hunan Province [SNRF2021]; Chief Scientist Office/the RS Macdonald Charitable Trust; [2022JJ50209]; [D202304117888]; [202210547020]

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本校为其他机构

摘要：

Trans-urocanic acid (UCA), an isomer of cis-UCA that is mainly located in the skin, has recently been reported to have a role in short-term working memory and in the consolidation, reconsolidation and retrieval of long-term memory. However, its effect on memory acquisition remains unclear. In the present study, the effect of UCA on short-term and long-term memory acquisition in mice was investigated using novel object recognition (NOR) and object location recognition (OLR) protocols that each involved three stages: habituation, sampling and testing. UCA was intraperitoneally injected 0.5h pre-...

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Urocanic acid facilitates acquisition of object recognition memory in mice

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