[Gong, Duo; Zhang, Min; Tang, Chao-Ke; Zhao, Zhen-Wang; Li, Liang; Yin, Wei-Dong; Xie, Wei] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Inst Cardiovasc Res, Key Lab Atherosclerol Hunan Prov,Med Res Ctr, Hengyang 421001, Hunan, Peoples R China.

[Lv, Yun-Cheng; Xie, Wei; Guo, Dong-ming] Univ South China, Clin Anat & Reprod Med Applicat Inst, Hengyang 421001, Hunan, Peoples R China.

[Li, Liang] Univ South China, Dept Pathophysiol, Hengyang 421001, Hunan, Peoples R China.

[Zheng, Xi-Long] Univ Calgary, Hlth Sci Ctr, Cumming Sch Med, Dept Biochem & Mol Biol,Libin Cardiovasc Inst Alb, 3330 Hosp Dr NW, Calgary, AB T2N 4N1, Canada.

[Zheng, Xi-Long] Guangzhou Med Univ, Sch Pharmaceut Sci, Key Lab Mol Targets & Clin Pharmacol, Guangzhou 511436, Guangdong, Peoples R China.

[Yin, WD; Tang, CK] U

Univ South China, Inst Cardiovasc Res, Hengyang 421001, Hunan, Peoples R China.

cholesterol;cholesterol ester;gypenoside;high density lipoprotein cholesterol;interleukin 1beta;interleukin 6;kruppel like factor 4;lipoprotein lipase;low density lipoprotein cholesterol;messenger RNA;microRNA;microRNA 27a;monocyte chemotactic protein 1;oxidized low density lipoprotein;tumor necrosis factor;unclassified drug;gypenoside;Klf14 protein, mouse;kruppel like factor;lipid;lipoprotein lipase;low density lipoprotein;microRNA;Mirn27 microRNA, mouse;plant extract;animal cell;animal experiment;animal model;animal tissue;aortic atherosclerosis;Article;atherosclerotic plaque;binding site;cell viability;cholesterol blood level;controlled study;cytokine release;down regulation;gene expression regulation;high density lipoprotein cholesterol level;human;human cell;human tissue;in vitro study;in vivo study;inflammation;lipid homeostasis;lipid metabolism;lipid storage;low density lipoprotein cholesterol level;macrophage function;male;mouse;mRNA expression level;nonhuman;peritoneum macrophage;priority journal;promoter region;protein expression level;THP-1 cell line;upregulation;animal;apolipoprotein E knockout mouse;atherosclerosis;chemistry;down regulation;genetic transfection;Gynostemma;homeostasis;lipid metabolism;macrophage;metabolism;pathology;RAW 264.7 cell line;Animals;Atherosclerosis;Down-Regulation;Gene Expression Regulation, Enzymologic;Gynostemma;Homeostasis;Kruppel-Like Transcription Factors;Lipid Metabolism;Lipids;Lipoprotein Lipase;Lipoproteins, LDL;Macrophages;Male;Mice;Mice, Knockout, ApoE;MicroRNAs;Plant Extracts;RAW 264.7 Cells;Transfection

医学院

药学与生物科学学院