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Integrative function of histone deacetylase 3 in inflammation

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成果类型:
期刊论文
作者:
Li, Junjie;Zhai, Yiyuan;Tang, Min
通讯作者:
Tang, M
作者机构:
[Li, Junjie; Tang, M; Tang, Min; Zhai, Yiyuan] Univ South China, Inst Biochem & Mol Biol, Hengyang Coll Med, Changsheng West Rd 28, Hengyang 421001, Peoples R China.
通讯机构:
[Tang, M ] U
Univ South China, Inst Biochem & Mol Biol, Hengyang Coll Med, Changsheng West Rd 28, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Inflammation;HDAC3;Deacetylation;Inflammatory signaling
期刊:
Molecular Biology Reports
ISSN:
0301-4851
年:
2024
卷:
51
期:
1
页码:
1-8
基金类别:
This work was funded by grants from National Natural Science Foundation of China (81711530050) and Hunan Provincial Education Department (20A418) to Drs Tang.
机构署名:
本校为第一且通讯机构
院系归属:
药学与生物科学学院
摘要:
Inflammation is a complex biological response triggered when an organism encounters internal or external stimuli. These triggers activate various signaling pathways, leading to the release of numerous inflammatory mediators aimed at the affected tissue. Ensuring precision and avoiding the excessive activation, the inflammatory process is subject to tight regulation. Histone deacetylase 3 (HDAC3), a member of class I HDACs family, stands out for its significant role in modulating various inflammatory signaling, including Nuclear Factor kappa B (...

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