期刊论文

中文

中华放射医学与防护杂志

0254-5098

2018

38

4

297-301

10.3760/cma.j.issn.0254-5098.2018.04.010

国家自然科学基金

本校为第一机构

目的基于三维剂量验证系统EDose~(TM),寻找食管癌调强放疗计划验证中利用γ分析方法判别计划是否通过的最佳阈值。方法回顾性地选取25例经临床批准的食管癌7野调强计划,使用Edose~(TM)在计划CT中重建三维剂量,并进行γ分析和剂量体积直方图(DVH)评价。然后,按照以下两个准则对计划分类:DVH特定剂量学指标绝对百分剂量差异90%,认为计划通过。根据分类结果绘制出受试者工作特征(receiver operating characteristic,ROC)曲线,通过计算约登系数的方式寻找全局γ在5%/3 mm、 3%/3 mm和2%/2 mm基准下的最佳通过率阈值,并对最佳阈值在计划判别中的敏感性和特异性进行分析。结果全局5%/3 mm、 3%/3 mm和...

Objective To investigate the optimal gamma passing rate of intensity-modulated radiotherapy (IMRT) dosimetric verification in the treatment of esophageal cancer using a three-dimensional dose verification system EDose~(TM). Methods Twenty five esophageal cancer patients treated by 7-field IMRT were retrospectively reviewed. Measured dose distribution were reconstructed on CT image and evaluated by gamma analysis and DVH metrics using the EDose~(TM) system. Plans with DVH metrics dose difference 90% under 3%/3 mm criteria were accepted. The optimal gamma passing rate for criteria of 5%/3 mm, 3%...