Effect of Intravenous Tirofiban Versus Placebo on First-Pass Successful Reperfusion in Endovascular Stroke Thrombectomy: Insights From the RESCUE BT Randomized Clinical Trial

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Yuan, Junjie;Ge, Hanming;Tao, Zhaojun;An, Huijie;Han, Qin;...

通讯作者：

Chang, MZ;Ruan, ZF

作者机构：

[Yuan, Junjie; Chen, Qiong; Qiu, Zhongming] Army Med Univ, Mil Med Univ 3, Xinqiao Hosp, Dept Neurol, Chongqing, Peoples R China.

[Yuan, Junjie; Chen, Qiong; Qiu, Zhongming] Army Med Univ, Mil Med Univ 3, Affiliated Hosp 2, Chongqing, Peoples R China.

[Yuan, Junjie] Gen Hosp Southern Theatre Command PLA, Dept Crit Care Med, Guangzhou, Peoples R China.

[Yuan, Junjie] Gen Hosp Southern Theatre Command PLA, Dept Anesthesiol, Guangzhou, Peoples R China.

[Yuan, Junjie; Wu, Fengfu] 925th Hosp Chinese Peoples Liberat Army, Dept Neurol, Guiyang, Peoples R China.

通讯机构：

[Ruan, ZF ] U

[Chang, MZ ] N

Northwest Univ, Xian Hosp 3, Affiliated Hosp, Dept Neurol, 10 East Sect Fengcheng 3rd Rd, Xian 710000, Peoples R China.

Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Neurol, 69 Chuanshan Ave, Hengyang 421001, Peoples R China.

语种：

英文

关键词：

acute ischemic stroke;anterior large‐vessel occlusion;endovascular therapy;first‐pass successful reperfusion;intravenous tirofiban

期刊：

Journal of the American Heart Association

年：

2024

卷：

期：

页码：

e036350

DOI：

10.1161/JAHA.124.036350

基金类别：

National Science Foundation of China [82301499]; Natural Science Foundation of Hunan Province [2023JJ60366]; Xi'an Science and Technology Plan Project [21YXYJ0004, 21YXYJ0052]; Natural Science Basic Research Project of Shaanxi Province [2022IM-452]

机构署名：

本校为通讯机构

院系归属：

医学院

摘要：

BACKGROUND: First-pass successful reperfusion (FPSR), defined as a successful/complete reperfusion achieved after a single thrombectomy pass, is predictive of favorable outcome in patients with acute ischemic stroke with large-vessel occlusion. It is unknown whether intravenous tirofiban is effective in increasing the rate of FPSR in acute anterior large-vessel occlusion stroke. METHODS AND RESULTS: Patients who had acute large-vessel occlusion stroke presenting within 24 hours and underwent endovascular thrombectomy were analyzed from the RESC...

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Effect of Intravenous Tirofiban Versus Placebo on First-Pass Successful Reperfusion in Endovascular Stroke Thrombectomy: Insights From the RESCUE BT Randomized Clinical Trial

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