Chlamydia,an obligate intracellular parasite organism with unique two-phase developmental cycle,could induce many human diseases.pORF5 protein is a cryptic plasmid-encoded secreted protein of Chlamydia.Recent years,it has been verified that pORF5 protein is the important virulence protein of Chlamydia,and it is closely related to the pathogenesis of Chlamydia.In this review,we will make a summary about the biological characteristics,inflammatory causing effect,anti-apoptosis eff...