A hybrid hydrogel within situformed Ag-nanoparticles within 3D networks that exhibits broad antibacterial activities

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成果类型：

期刊论文

作者：

Wei, Chuan-Wan;Gong, Xiao-Qing;Wang, Xiao-Juan*;Yang, Xin-Zhi;Gao, Shu-Qin;...

通讯作者：

Wang, Xiao-Juan;Lin, Ying-Wu

作者机构：

[Wei, Chuan-Wan; Gong, Xiao-Qing; Lin, Ying-Wu; Wang, Xiao-Juan; Wang, XJ] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.

[Wei, Chuan-Wan; Lin, Ying-Wu; Wang, Xiao-Juan; Wang, XJ] Univ South China, Hunan Key Lab Design & Applicat Actinide Complexe, Hengyang 421001, Peoples R China.

[Gao, Shu-Qin; Yang, Xin-Zhi; Lin, Ying-Wu] Univ South China, Lab Prot Struct & Funct, Hengyang 421001, Peoples R China.

通讯机构：

[Wang, XJ; Lin, YW; Lin, Ying-Wu] U

Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Peoples R China.

Univ South China, Hunan Key Lab Design & Applicat Actinide Complexe, Hengyang 421001, Peoples R China.

Univ South China, Lab Prot Struct & Funct, Hengyang 421001, Peoples R China.

语种：

英文

关键词：

Amino acids;Hydrogels;Irradiation;Medical applications;Metal nanoparticles;Ag nanoparticle;Anti-bacterial activity;Biomedical applications;Capping reagents;Hybrid hydrogels;Natural light;Silver nanoparticles (AgNps);UV irradiation;Silver nanoparticles;benzyl alcohol derivative;hydrogel;silver nanoparticle;tryptophan derivative;absorption;antibacterial activity;Article;cell viability;chemical structure;chirality;circular dichroism;controlled study;electron transport;Escherichia coli;gelation;human;human cell;MCF-7 cell line;nonhuman;oxidation reduction reaction;particle size;pH;priority journal;racemic mixture;room temperature;scanning electron microscopy;Staphylococcus aureus;Streptomyces albus;thermogravimetry;thermostability;thixotropy;transmission electron microscopy;ultrasound;ultraviolet irradiation;X ray photoemission spectroscopy

期刊：

NEW JOURNAL OF CHEMISTRY

ISSN：

1144-0546

年：

2020

卷：

期：

页码：

7265-7269

DOI：

10.1039/d0nj01128b

基金类别：

This work was financially supported by the NSFC of China (21807058), the Hunan Provincial Natural Science Foundation (2019JJ50492 and 2019JJ40259), the Hunan Provincial Education Foundation (18C0420), and the Doctoral scientific research foundation of USC (2014XQD32 and 2017XQD10).

机构署名：

本校为第一且通讯机构

院系归属：

化学化工学院

摘要：

A new hybrid hydrogel was constructed byin situforming silver nanoparticles (Ag NPs) within the 3D network of a hydrogel based on a tryptophan derivative containing a phenylcarbinol side group (HAIP), which was triggered by natural light, without the need of UV-irradiation or the addition of capping reagents. Remarkably, in addition to excellent thixotropy and injectability, the hybrid Ag NPs-HAIP hydrogel exhibits broad antibacterial activities without cell cytotoxicity, which makes it a potential candidate for various biomedical applications. © The Royal Society o...

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A hybrid hydrogel within situformed Ag-nanoparticles within 3D networks that exhibits broad antibacterial activities

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