Hypoxia/reoxygenation (H/r) injury in myocardial cells occurs frequently during cardiac surgery and affects the prognosis of patients. The present study aimed to investigate the protective effects of dexmedetomidine (dex) on H/r injury and its association with the c/eBP-homologous protein (cHoP) signaling pathway. an H/r model was constructed in H9c2 cells to investigate the effects of dex on H/r injury. cell viability, apoptosis and lactate dehydrogenase (LDH) levels were determined by MTT, flow cytometry and 2,4-dinitrophenylhydrazine colorim...
