期刊论文

Characteristics of HIV-1 transmitted drug resistance in Hunan Province,2021

中文

实用预防医学

1006-3110

2023

30

05

524-527

10.3969/j.issn.1006-3110.2023.05.003

国家科技重大专项(2017ZX10201101-002-009)；

本校为第一机构

目的 了解2021年湖南省HIV-1传播性耐药流行特征,为优化艾滋病抗病毒治疗提供数据支持。方法 招募湖南省2021年新报告的HIV-1感染者,从全血样本中提取HIV-1 DNA,采用PCR反应及Sanger测序获取po...展开更多 目的 了解2021年湖南省HIV-1传播性耐药流行特征,为优化艾滋病抗病毒治疗提供数据支持。方法 招募湖南省2021年新报告的HIV-1感染者,从全血样本中提取HIV-1 DNA,采用PCR反应及Sanger测序获取pol基因区段序列,序列上传至斯坦福HIV耐药数据库进行耐药分析。结果 共纳入348例未治疗患者,有334例成功测序,14例(4.2%,14/334)出现存在低度以上耐药的突变,其中13例(3.9%,13/334)有非核苷类反转录酶抑...

Objective To understand the epidemic characteristics of HIV-1 transmitted drug resistance in Hunan Province in 2021,and to provide data support for optimizing HIV antiretroviral therapy.Methods Newly reported people living with HIV-1 in Hunan Province in 2021 were recru...MORE Objective To understand the epidemic characteristics of HIV-1 transmitted drug resistance in Hunan Province in 2021,and to provide data support for optimizing HIV antiretroviral therapy.Methods Newly reported people living with HIV-1 in Hunan Province in 2021 were recruited.HIV-1 DNA was extracted from whole blood sample...