Objective To explore the relationship between the quality of life and hope, coping style in patients with breast caner. Methods Totally, 224 breast cancer patients were enrolled in the study and investigated with the general information questionnaire, Functional Assessment of Cancer Therapy- Breast (FACT- B, V4.0), Herth Hope Index (HHI) and Medical Coping Modes Questionnaire(MCMQ). The investigation items included the demographic data, the quality of life, the hope level and coping style of the patients. The data were analyzed by SPSS 17...