Objective To explore effect of Resveratrol on autophagy of Hep‐2 Cell and analysis of relative mecha‐nisms . Methods We apply western blotting and real time‐PCR to detect the protein levels .Intracellular reactive oxygen species (ROS) level was assessed by DCFH‐DA staining .All data are analyzed by using SPSS 13 software . Results Resveratrol promote Hep‐2 cells autophagy ,with 40 μM and 6 h in the most significant .It can increase the ratio of LC3 Ⅱ and LC3 I ,promoting the protein expression of beclin‐1 and the number of autophagic va...