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Research Progress and Future Development Potential of Oridonin in Pharmacological Activities

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成果类型:
期刊论文
作者:
Ye, Shiying;Sun, Shaowei;Cai, Jiye;Jiang, Jinhuan
通讯作者:
Jiang, J.
作者机构:
Institute of Pharmacy and Pharmacology, Hengyang Medical School, University of South China, Hengyang, Hunan, China
Department of Chemistry, Jinan University, Guangzhou 510632, China
Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hengyang Medical School, University of South China, Hengyang, Hunan, China
[Ye, Shiying] Institute of Pharmacy and Pharmacology, Hengyang Medical School, University of South China, Hengyang, Hunan, China
[Sun, Shaowei; Jiang, Jinhuan] Institute of Pharmacy and Pharmacology, Hengyang Medical School, University of South China, Hengyang, Hunan, China <&wdkj&> Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hengyang Medical School, University of South China, Hengyang, Hunan, China
通讯机构:
[Jiang, J.] H
Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hunan, China
语种:
英文
关键词:
anti-bacterial;anti-inflammatory;anti-oxidant;anti-tumor;Oridonin;pharmacological activities
期刊:
CURRENT MOLECULAR PHARMACOLOGY
ISSN:
1874-4672
年:
2023
卷:
16
期:
7
页码:
691-706
基金类别:
The funds in the content of the accepted documents include (The Scientific Research Fund of Hunan Provincial Education Department (Grant No. 20C1602), Hunan Natural Science Foundation of China for Young Scientists (Grant No.2021JJ40474). The Fund of Doctoral Initiation of University of South China (Grant No. 190XQD141)).
机构署名:
本校为第一机构
院系归属:
药学与生物科学学院
摘要:
In recent years, attention has increasingly focused on herbal medicines and their bioactive components attributed to their multi-target pharmacological activity and low side effects. Oridonin is a natural diterpenoid extracted from the traditional Chinese herb and is one of the main active components of Rabdosia rubescens. Modern pharmacological studies have shown that oridonin has anti-tumor, anti-bacterial, anti-inflammatory, anti-oxidant, cardiovascular protective, immunomodulatory, and other effects. Based on the published literature in rec...

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