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CBCT-based synthetic CT generated using CycleGAN with HU correction for adaptive radiotherapy of nasopharyngeal carcinoma

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成果类型:
期刊论文
作者:
Chen, Jihong;Quan, Kerun;Chen, Kaiqiang;Zhang, Xiuchun;Zhou, Yimin;...
通讯作者:
Bai, PG
作者机构:
[Chen, Jihong; Chen, Kaiqiang; Bai, Penggang; Zhang, Xiuchun] Fujian Med Univ, Fujian Canc Hosp, Dept Radiat Oncol, Clin Oncol Sch, Fuzhou 350014, Fujian, Peoples R China.
[Quan, Kerun] Xiangtan City Cent Hosp, Dept Radiat Oncol, Xiangtan 411100, Hunan, Peoples R China.
[Zhou, Yimin] Univ South China, Sch Nucl Sci & Technol, Hengyang 421001, Peoples R China.
通讯机构:
[Bai, PG ] F
Fujian Med Univ, Fujian Canc Hosp, Dept Radiat Oncol, Clin Oncol Sch, Fuzhou 350014, Fujian, Peoples R China.
语种:
英文
期刊:
Scientific Reports
ISSN:
2045-2322
年:
2023
卷:
13
期:
1
页码:
6624
基金类别:
Joint Funds for the innovation of science and Technology, Fujian province [2021Y9190]; Science and Technology Project of Fujian Province [2021Y0052, 2022Y0056]; Startup Fund for scientific research, Fujian Medical University [2020QH1223]; Fujian Provincial Health Technology Project [2021CXB013]; Fujian Provincial Clinlical Research Center for Cancer Radiotherapy and Immunotherapy [2020Y2012]
机构署名:
本校为其他机构
院系归属:
核科学技术学院
摘要:
This study aims to utilize a hybrid approach of phantom correction and deep learning for synthesized CT (sCT) images generation based on cone-beam CT (CBCT) images for nasopharyngeal carcinoma (NPC). 52 CBCT/CT paired images of NPC patients were used for model training (41), validation (11). Hounsfield Units (HU) of the CBCT images was calibrated by a commercially available CIRS phantom. Then the original CBCT and the corrected CBCT (CBCT_cor) were trained separately with the same cycle generative adversarial network (CycleGAN) to generate SCT1 and SCT2. The mean error and mean absolute error ...

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