Some 2-D and 3-D graphical representation of DNA sequences have been given by Nandy, Leong and Mogenthaler, and Randic et al., which give visual characterizations of DNA sequences, and a number of different approaches have been developed to date on numerically characterizing DNA sequences, but application of such method to practical problems still remains a formidable task. In this paper, we presented a novel graphical representation of DNA sequences by taking four special vectors in 2D Cartesian coordinate system to represent the four nucleic acid bases in DNA sequences, so that a DNA sequenc...