期刊论文

Effects of Ultra - fine Powder Technique on Dissolution Rates of Flavonoids in Frutus Aurantii Immaturus （Cirtus aurantium L. ）

中文

广州化工

1001-9677

2012

40

17

48-50

10.3969/j.issn.1001-9677.2012.17.020

广东省教育部产学研结合项目（No.2009B090200054）； 南华大学***启动基金项目（2011XQD47）；

本校为第一机构

探讨了超微粉碎对枳实药材中有效成分溶出率的影响。以0.05%磷酸水-甲醇-乙腈为流动相,采用高效液相色谱法（high performance liquid chromatography,HPLC）测定枳实超微粉与药材60目细粉中橙皮苷、柚皮苷和芸香柚皮苷的溶出率。结果表明,枳实超微粉中的橙皮苷、柚皮苷和芸香柚皮苷的溶出率明显高于其60目细粉中三者的溶出率,超微粉碎可增强枳实药材有效成分的溶出。

The effects of ultra - fine powder technique on dissolution rates of the flavonoids in Frutus Aurantii lmmaturus （FAI） were explored. Using 0. 05% H3PO4 water solution -CH3OH -CH3CN as mobile phase, high performance liquid chromatography was employed to determine the concentration of hesperidin, naringin and narirutin in common powdered and ultra - fine powdered FAI. The results were that the dissolution rates of hesperidin, naringin and narirutin in ultra - fine powdered FAI were higher than those of the general powder, and ultra - fine powder technique promot...