Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and the risk of early-onset post-stroke depression: a prospective study

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Deng, Mingzhu;Song, Kangping;Gao, Lichen;Wang, Zhen;Zhao, Wei;...

通讯作者：

Li, FY

作者机构：

[Deng, Mingzhu] Second Peoples Hosp Hunan Prov, Brain Hosp Hunan Prov, Dept Neurol, Changsha, Hunan, Peoples R China.

[Zhao, Wei; Song, Kangping; Li, Fangyi; Wang, Zhen; Feng, Tieqiao; Xu, Wei] Univ South China, Affiliated Changsha Cent Hosp, Hengyang Med Sch, Dept Neurol, Changsha, Hunan, Peoples R China.

[Gao, Lichen] Univ South China, Affiliated Changsha Cent Hosp, Phase Clin Trial Ctr 1, Sch Pharm,Dept Pharm,Hengyang Med Sch, Changsha, Peoples R China.

通讯机构：

[Li, FY ] U

Univ South China, Affiliated Changsha Cent Hosp, Hengyang Med Sch, Dept Neurol, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

abnormal lipid metabolism;acute ischemic stroke;depression;non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio;post-stroke depression

期刊：

FRONTIERS IN NEUROLOGY

ISSN：

1664-2295

年：

2025

卷：

页码：

1645765

DOI：

10.3389/fneur.2025.1645765

基金类别：

Natural Science Foundation of Hunan Province [2023JJ40072]; Science and Technology Planning Project of Hunan Health Committee [D202303076376]

机构署名：

本校为通讯机构

院系归属：

医学院

药学与生物科学学院

摘要：

Background: The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is a recently developed composite indicator of atherogenic lipids. Nevertheless, few studies concern the relationship between NHHR and early-onset post-stroke depression (PSD). Methods: After two weeks of acute ischemic stroke (AIS), early-onset PSD was identified. The Hamilton Depression Scale-17 items (HAMD-17) was used to assess the severity of depression. Patients with HAMD-17 scores ≥7 were divided into an early-onset PSD group. S...

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Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and the risk of early-onset post-stroke depression: a prospective study

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