Background Aortic dissection（AD） is a lethal medical emergency, which lacks specific biomarkers and effective pharmaceutical therapies. Increasing evidences have shown beneficial effect of angiotensin receptor blocker（ARB） drugs on downregulating transforming growth factor-β（TGF-β） pathway in Marfanoid AD. However,for non-Marfanoid AD, the effectiveness of ARB drugs, as well as the possible mechanisms, remains unclear.Methods Sprague Dawley（SD） rats were fed by gavage（i.g.） with either 150 mg/（kg·d） Hydroxyethyl diamine（AEEA） o...
