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Engineering an upconversion fluorescence sensing platform with "off-on" pattern through specific DNAzyme-mediated signal amplification for supersensitive detection of uranyl ion

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成果类型:
期刊论文
作者:
Zhang, Xinyu;Wang, Yue;Gong, Mi;Xiong, Lihao;Song, Jiayi;...
通讯作者:
Chen, Sihan;Li, Le;Zhen, DS
作者机构:
[Li, Le; Chen, Sihan; Zhen, Deshuai; Zhen, DS; Xiong, Lihao; Gong, Mi; Zhang, Xinyu; Wang, Yue; Tong, Yuqi; Song, Jiayi] Univ South China, Coll Publ Hlth, Hengyang Med Sch, Hunan Key Lab Typ Environm Pollut & Hlth Hazards, Hengyang 421001, Peoples R China.
[Liu, Yu; Zhen, Deshuai; Zhen, DS] Hunan Univ, State Key Lab Chemo Biosensing & Chem Engn, Changsha 410082, Peoples R China.
通讯机构:
[Li, L; Chen, SH; Zhen, DS ] U
Univ South China, Coll Publ Hlth, Hengyang Med Sch, Hunan Key Lab Typ Environm Pollut & Hlth Hazards, Hengyang 421001, Peoples R China.
Hunan Univ, State Key Lab Chemo Biosensing & Chem Engn, Changsha 410082, Peoples R China.
语种:
英文
关键词:
Upconversion nanoparticles;Fluorescence resonance energy transfer;Uranyl;Deoxyribozyme;Hybrid chain reaction
期刊:
Microchimica Acta
ISSN:
0026-3672
年:
2024
卷:
191
期:
8
页码:
1-11
基金类别:
This work was supported by the grant from the National Natural Science Foundation of China (82204176, 12175103, 12305389); the Natural Science Foundation of Hunan Province (2023JJ50127, 2024JJ5345); the Major Science and Technology Public Relations Project in Hunan Province (2023ZK1060), and the research fund of Nuclear Materials of China Atomic Energy Authority (WDZC-2023-AW-0322).
机构署名:
本校为第一且通讯机构
院系归属:
公共卫生学院
摘要:
Anupconversion fluorescence sensing platform was developedwith upconversion nanoparticles (UCNPs) as energy donors and gold nanoparticles (AuNPs) as energy acceptors, based on the FRET principle. They were used for quantitativedetection ofuranyl ions (UO(2)(2+)) by amplifying the signal of the hybrid chain reaction (HCR). When UO(2)(2+) are introduced, the FRET between AuNPs and UCNPs can be modulated through a HCR in the presence of high concentrations of sodium chloride. This platform providesexceptional sensitivity, with a detection limit as low as 68pM for UO(2)(2+) recognition. We have su...

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