Analysis of the miRNA expression profile of laboratory red crucian carp under low-dose caesium-137 irradiation

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成果类型：

期刊论文

作者：

Wang, Yude;Liao, Xiao-Li;Chen, KeJie;Zhang, Zhaohui;Liu, Yuxin;...

通讯作者：

DuanSheng Wu

作者机构：

[Liu, Yuxin; Wu, DuanSheng; Wang, Yude; Yang, JingPing] Hunan Normal Univ, Coll Life Sci, State Key Lab Dev Biol Freshwater Fish, Changsha 410081, Peoples R China.

[Liao, Xiao-Li] Hunan Inst Traff Engn, Sch Med Technol & Nursing, Hengyang 421001, Peoples R China.

[Zhang, Zhaohui; Chen, KeJie; Wu, DuanSheng; Liao, Xiao-Li] Univ South China, Hengyang Med Coll, Hengyang 421001, Peoples R China.

[Zhang, Zhaohui; Chen, KeJie; Wu, DuanSheng; Liao, Xiao-Li] Univ South China, Dept Lab Anim Sci, Hengyang 421001, Peoples R China.

通讯机构：

[DuanSheng Wu] S

State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University, Changsha, China<&wdkj&>University of South China, Hengyang Medical College, Hengyang, China<&wdkj&>University of South China, Department of Laboratory Animal Science, Hengyang, China

语种：

英文

关键词：

Laboratory red crucian carp;Irradiation;MicroRNA

期刊：

Ecotoxicology

ISSN：

0963-9292

年：

2022

卷：

期：

页码：

1276-1286

DOI：

10.1007/s10646-022-02578-8

基金类别：

This work was supported by the Natural Science Foundation of Hunan Province (Grant nos. 2019JJ40077, 2021JJ40344). Funds for this project provide funding for reagents, consumables, and laboratory apparatus for this study.

机构署名：

本校为其他机构

院系归属：

药学与生物科学学院

摘要：

Abstract: Radiation can cause the differential expression of biological miRNA molecules. This research was based on the development of the laboratory red crucian carp (LRCC) to explore the feasibility of its application in the detection of low-dose ionizing radiation-induced biological damage in aquatic environments and the development of related molecular markers. Adult LRCC were irradiated with caesium-137 at 0.3 Gy, while RNA-seq and bioinformatics techniques were used to identify miRNAs that were differentially expressed relative to their l...

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Analysis of the miRNA expression profile of laboratory red crucian carp under low-dose caesium-137 irradiation

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