Pre-treatment serum alkaline phosphatase and lactate dehydrogenase as prognostic factors in triple negative breast cancer

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成果类型：

期刊论文

作者：

Chen, Bo;Dai, Danian;Tang, Hailin;Chen, Xi;Ai, Xiaohong;...

通讯作者：

Wei, Weidong;Xie, Xiaoming

作者机构：

[Wei, Weidong; Dai, Danian; Tang, Hailin; Xie, Xiaoming; Huang, Xiaojia; Chen, Bo] Sun Yat Sen Univ, Canc Ctr, Collaborat Innovat Ctr Canc Med, Dept Breast Oncol,State Key Lab Oncol South China, Guangzhou, Guangdong, Peoples R China.

[Chen, Xi] Univ South China, Coll Med, Dept Anat, Hengyang, Hunan, Peoples R China.

[Ai, Xiaohong] Univ South China, Affiliated Hosp 1, Dept Radiotherapy, Hengyang, Hunan, Peoples R China.

[Wei, WD; Xie, XM] Sun Yat Sen Univ, Ctr Canc, Dept Breast Oncol, 651 East Dongfeng Rd, Guangzhou 510060, Guangdong, Peoples R China.

通讯机构：

[Wei, WD; Xie, XM] S

Sun Yat Sen Univ, Ctr Canc, Dept Breast Oncol, 651 East Dongfeng Rd, Guangzhou 510060, Guangdong, Peoples R China.

语种：

英文

关键词：

Alkaline phosphatase;Biomarker.;Lactate dehydrogenase;Prognostic factor;Triple negative breast cancer

期刊：

JOURNAL OF CANCER

ISSN：

1837-9664

年：

2016

卷：

期：

页码：

2309-2316

DOI：

10.7150/jca.16622

基金类别：

Science and Technology Planning Projects of Guangdong and Guangzhou [2013B060300009, 2015B020211002, 2014A020212079, 2015B090901050, 2013B021800072, 2014J4100169]; Guangdong Natural Science FoundationNational Natural Science Foundation of Guangdong Province [S2012010008521]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81272514, 81472575, 81372133, 81472469]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Background: Serum parameters as prognostic parameters are studied widely. We aim to examine the prognostic significance of the serum alkaline phosphatase (ALP) level and lactate dehydrogenase (LDH) level in triple negative breast cancer (TNBC). Methods: Total of 253 TNBC patients from Sun Yat-sen University Cancer Center who underwent treatment between January 2004 and December 2009 was conducted in this retrospective study. Before treatment serum ALP and LDH levels were routinely measured. We use the receiver operating characteristic (ROC) cur...

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Pre-treatment serum alkaline phosphatase and lactate dehydrogenase as prognostic factors in triple negative breast cancer

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