Clinical application of serum-based proteomics technology in human tumor research

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Li, Chen;Xiao, Juan;Wu, Shihua;Liu, Lu;Zeng, Xuemei;...

通讯作者：

Zhao, Qiang(276020102@qq.com);Zhang, Zhiwei(nhdxzzw@qq.com)

作者机构：

[Li, Chen; Zhao, Qiang; Zhang, Zhiwei; Liu, Lu] Univ South China, Dept Pathol, Affiliated Hosp 1, Hengyang 421001, Hunan, Peoples R China.

[Xiao, Juan] Univ South China, Dept Otorhinolaryngol, Affiliated Hosp 2, Hengyang 421001, Hunan, Peoples R China.

[Wu, Shihua] Second Hosp Shaoyang Coll, Dept Pathol, Hunan, Shaoyang 422000, Hunan, Peoples R China.

[Zhang, Zhiwei; Zeng, Xuemei] Univ South China, Canc Res Inst, Key Lab Canc Cellular & Mol Pathol Hunan Prov, Hengyang Med Coll, Hengyang 421001, Hunan, Peoples R China.

[Zhao, Qiang] Univ South China, Dept Pathol, Affiliated Hosp 1, 69 Chuanshan Rd, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Qiang Zhao; Zhiwei Zhang] D

Q. Zhao

Department of Pathology, The First Affiliated Hospital of University of South China, Hengyang, 69 Chuanshan Road, Hunan, 421001, China

email: 276020102@qq.com

Z. Zhang

语种：

英文

关键词：

Biomarkers, Tumor;Humans;Neoplasms;Proteome;Proteomics;Serum;Technology;Biomedical engineering;Clinical research;Molecular biology;Proteins;Tumors;plasma protein;proteome;tumor marker;proteome;tumor marker;Clinical application;Dynamic changes;Human serum;Human tumors;Human understanding;Pathological conditions;Physiological condition;Proteomic technologies;Serum;Supporting role;breast cancer;cancer research;clinical practice;colorectal cancer;extraction;hematologic malignancy;human;human tissue;liquid chromatography-mass spectrometry;liver cancer;lung cancer;matrix assisted laser desorption ionization time of flight mass spectrometry;prostate cancer;proteomics;Review;serum;stomach cancer;two dimensional gel electrophoresis;neoplasm;technology;Biomarkers

期刊：

Analytical Biochemistry

ISSN：

0003-2697

年：

2023

卷：

663

页码：

115031

DOI：

10.1016/j.ab.2022.115031

基金类别：

Innovation and Entrepreneurship Training Program for College Students in Hunan Province, (S202110555296) Key Projects of Hunan Provincial Education Department, (21A0285) Natural Science Foundation of Hunan Provincial and Municipal Co-funding, (2022JJ50029) Natural Science Foundation ofHunan Province, (2020JJ4083, 2021JJ30694) Natural Science Foundation ofHunan Province Shenyang Science and Technology Bureau, (2021GZ031) Shenyang Science and Technology Bureau National Key Research and Development Program of China, NKRDPC, (2021YFE0192100) National Key Research and Development Program of China, NKRDPC Science and Technology Program of Hunan Province, (2020SK51703) Science and Technology Program of Hunan Province

机构署名：

本校为第一机构

院系归属：

医学院

摘要：

The rapid development of proteomics technology in the past decades has led to further human understanding of tumor research, and in some ways, the technology plays a very important supporting role in the early detection of tumors. Human serum has been shown to contain a variety of proteins closely related to life activities, and the dynamic change in proteins can often reflect the physiological and pathological conditions of the body. Serum has the advantage of easy extraction, so the application of proteomics technology in serum has become a h...

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Clinical application of serum-based proteomics technology in human tumor research

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