Isolation and Characterization of Avian Chlamydia psittaci from Symptomatic Pet Birds in Southern Hunan, China

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成果类型：

期刊论文

作者：

Wang, Chuan;Li, Li;Xie, Yafeng;Tan, Yuan;Wen, Yating;...

通讯作者：

Wu, Yimou

作者机构：

[Yu, Jian; Wu, Yimou; Li, Li; Song, Ying; Xie, Yafeng; Tan, Yuan; Wen, Yating; Wang, Chuan; Chen, Qian] Univ South China, Inst Pathogen Biol, Med Coll, Hunan Prov Key Lab Special Pathogens Prevent & Co, Hengyang 421001, Peoples R China.

[Yu, Jian; Wu, Yimou; Li, Li; Song, Ying; Xie, Yafeng; Tan, Yuan; Wen, Yating; Wang, Chuan; Chen, Qian] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Med Coll, Hengyang 421001, Peoples R China.

[Yu, Jian] Univ South China, Med Coll, Dept Expt Zool, Hengyang 421001, Peoples R China.

通讯机构：

[Wu, Yimou] U

Univ South China, Inst Pathogen Biol, Med Coll, Hunan Prov Key Lab Special Pathogens Prevent & Co, Hengyang 421001, Peoples R China.

Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Med Coll, Hengyang 421001, Peoples R China.

语种：

英文

关键词：

animal;bird;C57BL mouse;cell line;China;Chlamydia psittaci;Chlorocebus aethiops;female;genetics;germfree animal;human;isolation and purification;microbiology;mouse;ornithosis;pet animal;species difference;Vero cell line;Animals;Birds;Cell Line;China;Chlamydophila psittaci;Chlorocebus aethiops;Female;Humans;Mice;Mice, Inbred C57BL;Pets;Psittacosis;Species Specificity;Specific Pathogen-Free Organisms;Vero Cells

期刊：

AVIAN DISEASES

ISSN：

0005-2086

年：

2019

卷：

期：

页码：

31-37

DOI：

10.1637/11932-071718-Reg.1

基金类别：

This work was supported by the National Natural Science Foundation of China under grant 81671986, by the Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control Foundation under grant 2014-5, and by the Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study (2015-351).

机构署名：

本校为第一且通讯机构

院系归属：

医学院

药学与生物科学学院

摘要：

Chlamydia psittaci is a zoonotic pathogen with multiple hosts, especially avian, and can be transmitted to humans, causing psittacosis or ornithosis. No effective vaccines have been developed. We therefore isolate and genotype avian C. psittaci strains and investigate the pathogenicity of isolates in the southern Hunan area of China. Among 200 suspicious avian specimens, eight were positive for the C. psittaci outer membrane protein A (ompA) gene (4%), and seven were successfully cultured in human epithelial type 2 and Vero cells (87.5%). Genot...

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Isolation and Characterization of Avian Chlamydia psittaci from Symptomatic Pet Birds in Southern Hunan, China

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