Prognostic significance of TCF21 mRNA expression in patients with lung adenocarcinoma

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成果类型：

期刊论文

作者：

Xiao, Jian;Liu, Aibin;Lu, Xiaoxiao;Chen, Xi;Li, Wei;...

通讯作者：

Chen, Qiong

作者机构：

[He, Bixiu; Lu, Xiaoxiao; Chen, Qiong; Xiao, Jian] Cent S Univ, Xiangya Hosp, Dept Geriatr, Resp Med, Changsha, Hunan, Peoples R China.

[Liu, Aibin] Cent S Univ, Xiangya Hosp, Dept Geriatr, Changsha, Hunan, Peoples R China.

[Chen, Xi] Cent S Univ, Xiangya Hosp, Dept Resp Med, Changsha, Hunan, Peoples R China.

[Li, Wei] Cent S Univ, Xiangya Hosp, Dept Geriatr, Clin Lab, Changsha, Hunan, Peoples R China.

[He, Shuya] Univ South China, Dept Biochem & Biol, Hengyang, Peoples R China.

通讯机构：

[Chen, Qiong] C

Cent S Univ, Xiangya Hosp, Dept Geriatr, Resp Med, Changsha, Hunan, Peoples R China.

语种：

英文

期刊：

Scientific Reports

ISSN：

2045-2322

年：

2017

卷：

期：

页码：

2027

DOI：

10.1038/s41598-017-02290-2

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81572284]; Important Research and Development Plan of Hunan Provincial Science and Technology Department [2015SK20662]

机构署名：

本校为其他机构

院系归属：

药学与生物科学学院

摘要：

Several prognostic indicators have shown inconsistencies in patients of different genders with lung adenocarcinoma, indicating that these variations may be due to the different genetic background of males and females with lung adenocarcinoma. In this study, we first used the Gene-Cloud of Biotechnology Information (GCBI) bioinformatics platform to identify differentially expressed genes (DEGs) that eliminated gender differences between lung adenocarcinoma and normal lung tissues. Then, we screened out that transcription factor 21 (TCF21) is a hub gene among these DEGs by creating a gene co-exp...

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Prognostic significance of TCF21 mRNA expression in patients with lung adenocarcinoma

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