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Relationship between plasma lipid concentrations and HDL subclasses

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成果类型:
期刊论文
作者:
Yang, YY;Yan, BY;Fu, MD*;Xu, YH;Tian, Y
通讯作者:
Fu, MD
作者机构:
[Fu, MD] Sichuan Univ, W China Sch Preclin & Forens Med, Apolipoprot Res Unit, Dept Biochem & Mol Biol, Chengdu 610041, Sichuan, Peoples R China.
Postdoctoral Work Stn, Hoist Grp, Chengdu, Sichuan, Peoples R China.
Nanhua Univ, Dept Biochem & Mol Biol, Hengyang, Hunan, Peoples R China.
通讯机构:
[Fu, MD] S
Sichuan Univ, W China Sch Preclin & Forens Med, Apolipoprot Res Unit, Dept Biochem & Mol Biol, Chengdu 610041, Sichuan, Peoples R China.
语种:
英文
关键词:
Apo-AI containing HDL subclasses;High-density lipoprotein-cholesterol;Low-density lipoprotein-cholesterol;Total cholesterol;Triglyceride;Two-dimensional gel electrophoresis-immunodetection
期刊:
Clinica Chimica Acta
ISSN:
0009-8981
年:
2005
卷:
354
期:
1-2
页码:
49-58
基金类别:
This work was supported by China Medical Board of New York (No.82-412). The authors thank Professor Bingwen Liu, technician Yu Liu, Master students Jiao Yao and Xuemei Zhang for the collection of blood sample and technical support in lipid and apolipoprotein assays.
机构署名:
本校为其他机构
院系归属:
化学化工学院
药学与生物科学学院
摘要:
Background: It is generally accepted that different high-density lipoprotein (HDL) subclasses have distinct but interrelated metabolic functions. HDL is known to directly influence the atherogenic process and changes in HDL subclasses distribution may be related to the incidence and prevalence of atherosclerosis. Methods: Apo-AI contents(mg/l) of plasma HDL subclasses were determined by 2-dimensional gel electrophoresis coupled with immunodetection for apo-AI. Four hundred forty-two Chinese adults subjects aged 33 to 78 years were assigned to d...

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