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Early effectiveness and safety analysis of belimumab in addition to standard treatment in patients with systemic lupus erythematosus

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成果类型:
期刊论文
作者:
He, Lingyan;Yan, Mingming;Wen, Rui;Li, Jiali
通讯作者:
Li, JL
作者机构:
[Li, Jiali; He, Lingyan; Wen, Rui; Li, JL] Univ South China, Dept Rheumatol & Immunol, Changsha Cent Hosp, Changsha, Hunan, Peoples R China.
[Yan, Mingming] Cent South Univ, Xiangya Hosp 2, Dept Orthopaed Surg, Changsha, Hunan, Peoples R China.
通讯机构:
[Li, JL ] U
Univ South China, Dept Rheumatol & Immunol, Changsha Cent Hosp, Changsha, Hunan, Peoples R China.
语种:
英文
关键词:
Belimumab;clinical improvement;early effectiveness;prednisone;safety;systemic lupus erythematosus
期刊:
Archives of Rheumatology
ISSN:
2148-5046
年:
2024
机构署名:
本校为第一且通讯机构
摘要:
Objectives: This study aimed to evaluate the early effectiveness and safety of belimumab in addition to standard therapy in patients with systemic lupus erythematosus (SLE) for 24 weeks. Patients and methods: This retrospective study was conducted with 60 adult patients with active SLE between June 2020 and August 2022. The patients either received intravenous belimumab in addition to standard therapy (n=31; 24 females, 7 males; mean age: 33.7 +/- 14.1 years; range, 18 to 52 years) or only standard therapy (n=29; 22 females, 7 males; mean age: 34.1 +/- 13.4 years; range, 19 to 66 years) for 24...

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