Effects of Low-Dose Gamma-Ray Radiation on Apoptosis and Development of Zebrafish Embryo Brain

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成果类型：

期刊论文

作者：

Zhao, Weichao;Yuan, Penghui;Hu, Nan;Long, Dingxin;Ding, Dexin*;...

通讯作者：

Ding, Dexin

作者机构：

[Ding, Dexin; Wang, Huimin; Yuan, Penghui; Hu, Nan; Zhao, Weichao] Univ South China, Key Discipline Lab Natl Def Biotechnol Uranium Mi, Hengyang 421001, Hunan, Peoples R China.

[Ding, Dexin; Wang, Huimin; Yuan, Penghui; Hu, Nan] Hunan Prov Key Lab Green Dev Technol Extremely Lo, Hengyang 421001, Hunan, Peoples R China.

[Long, Dingxin; Zhao, Weichao] Univ South China, Sch Publ Hlth, Hengyang 421001, Hunan, Peoples R China.

[Ding, Dexin] Univ South China, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Ding, Dexin] U

Univ South China, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

期刊：

RADIATION RESEARCH

ISSN：

0033-7587

年：

2020

卷：

194

期：

页码：

61-70

DOI：

10.1667/RR15426.1

基金类别：

Defense Industrial Technology Development Program [JCKY2016403C001]

机构署名：

本校为第一且通讯机构

院系归属：

核资源工程学院

公共卫生学院

摘要：

To investigate the effects of low-dose gamma irradiation on apoptosis and development of the brain in zebrafish embryos, cumulative 15 mGy doses of gamma rays from a Cs-137 source were used to irradiate zebrafish embryos at 2 h post-fertilization (hpf) for 120 h. Apoptosis of the brain, brain morphological development, cell submicroscopic structure and mRNA expression were analyzed, respectively. Results indicate that after 15 mGy exposure, the apoptosis of zebrafish brain increased, vacuoles appeared in brain tissue, some organdies were damaged and vacuoles appeared locally in brain cells. Th...

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Effects of Low-Dose Gamma-Ray Radiation on Apoptosis and Development of Zebrafish Embryo Brain

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