期刊论文

Zhou, Jie

英文

Cellular and Molecular Life Sciences

1420-682X

2019

76

22

4503-4510

10.1007/s00018-019-03228-9

This work was supported by the following grants to J. Zhou: National Natural Science Foundation of China (Nos. 91542112; 81571520; 81771665; 81742002), Start-up Fund for High-level Talents of Tianjin Medical University, Science and Technology Program of Guangzhou (No. 201707010452), Natural Science Foundation of Guangdong Province (No. 2017B030311014). It was also supported by National Natural Science Foundation of China (No. 81800031 to A. Lei), Natural Science Foundation of Guangdong Province (No. 2018A030313648 to A. Lei) and Research Foundation of Education Bureau of Human Province, China (No. 18C0458).

本校为第一机构

Group 2 innate lymphoid cells (ILC2s) are a subset of innate immune cells that do not express antigen receptors. ILC2-mediated type 2 responses, which are mainly characterized by the production of interleukin (IL)-5 and IL-13, play key roles in inducing inflammation, protecting against infection, and maintaining tissue homeostasis. Although recent years have largely enhanced our understanding of the transcriptional networks and soluble mediators that regulate ILC2 development or function, emerging evidence suggests that ILC2s express a variety ...